HER2 and uPAR cooperativity contribute to metastatic phenotype of HER2-positive breast cancer.

Oncoscience · 2015 · PMC4394126 · PMID 25897424

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highly significantno p-value reported

[ 120 ] demonstrated uPAR to be a highly significant crosstalk molecule that is necessary for the activation of signal transducer and activator of transcription 5b (STAT5b), a recently identified downstream effector of EGFRvIII [ 121 ], in glioblastoma multiforme cells.

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