Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing.

Nat Commun · 2015 · PMC4394211 · PMID 25858675

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For upregulated transcripts, the 1-month post-DSB livers showed more overlap with normal old mouse liver than the 2-month post-DSB livers, with a small, but highly significant overlap of 29 genes that were upregulated in all three groups ( Fig. 6d ).

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