Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.

J Cell Biol · 2015 · PMC4395491 · PMID 25869668

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at the limit of significanceno p-value reported

The steady-state levels of PIs in Sac2 KO MEFs, as measured by HPLC of metabolically labeled cells, demonstrated only a very minor (∼5%, and at the limit of significance) increase in PI4P (PI4P levels expressed as the percentage of total detectable PIs in wild-type (WT) control and KO MEFs were 0.058 ± 0.0010 and 0.061 ± 0.0012 [P < 0.375], respectively).

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