Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls.

Though the cut-point of ≥ 1 CTC/7.5 mL did not achieve significance between the two groups, a cut-point of ≥ 2 CTCs/7.5 mL was significant, positive in 7/20 (35%) HCC patients compared with none in the NMLD cohort ( p = 0.04), consistent with prior reports [ 14 , 15 ].

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