Recently, a human GWAS reported a highly significant association between LPCAT3 and the phospholipid composition of red blood cell membranes, indicating that Lpcat3 is also a key regulator of phospholipid composition in humans ( Tintle et al., 2014 ).
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Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion.
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