In premenopausal women (Table 3 ), we also observed 0.37 SD lower, yet borderline significant, ESR1 expression among the highly obese (adjusted mean difference = −0.96; 95% CI: −1.97, 0.05), while ESR1 expression was 1.5 SD significantly lower among the underweight (adjusted mean difference = −3.90; 95% CI: −6.44, −1.36).
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Association of high obesity with PAM50 breast cancer intrinsic subtypes and gene expression.
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