Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy.

Clin Epigenetics · 2015 · PMC4405830 · PMID 25904990

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a weak trendno p-value reported

For cells from each of three FSHD donors, the frequency of DUX4-FL-positive nuclei showed a weak trend to lower frequency of expression at higher passages and population doublings ( R 2 = 0.16 for 07Abic, 0.32 for 09Abic, and 0.39 for 17Abic).

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