Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks.

Of particular interest, the core and shell sub-regions of the NAc, as well as the VTA, showed a highly significant fraction of overlapping MRs ( P <0.01), suggesting that some common neuroadaptations may affect elements of the reward-motivational systems (Additional file 1 : Tables S2a and b).

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