Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa.

Nat Commun · 2015 · PMC4410645 · PMID 25897488

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highly significantno p-value reported

We find that this plasmid produces a highly significant impact on the transcriptional profile of the host, including the induction of the SOS response via the expression of the plasmid replication protein gene rep .

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