Compared with no α-syn mAb treatment, we observed a highly significant reduction of α-syn pathology in C1 and C2 at 7 and 14 days following treatment with Syn211 and Syn303 ( Figures S3B–S3D ).
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Α-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration.
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