DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density.

Oncotarget · 2015 · PMC4414142 · PMID 25682867

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hedged sentences

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closest p

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of borderline significanceno p-value reported

Applying this strategy to investigate the role of RRBS-measured DNA methylation initially yielded only results of borderline significance (Figure 8A ).

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highly significantno p-value reported

Overall, these highly significant results illustrate a genome-wide age-related drift away from intermediate toward either high or low levels of methylation.

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