MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma.

Oncotarget · 2015 · PMC4414152 · PMID 25738367

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highly significantno p-value reported

Furthermore, there is a highly significant correlation between levels of miR-10b and E2F1 transcripts across the TCGA GBM dataset (Figure 1 and Table 1 ), regardless of p21 expression. miR-10b regulates the levels and activities of the miR-15/16 cluster Among the transcripts most affected by the inhibition of miR-10b in A172 and U87 cells, we identified miR-15/16.

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