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The development of drug resistance mutations K103N Y181C and G190A in long term Nevirapine-containing antiviral therapy.

AIDS Res Ther · 2014 · PMC4414387 · PMID 25926857

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an increasing trendno p-value reported
In the follow-up time points, K103N showed a decreasing trend and G190A showed an increasing trend, while Y181C maintained dominant.

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a decreasing trendno p-value reported
In the patient HENDRC593, the frequency of K103N showed a decreasing trend, especially from 44.8 months, the K103N vanished in SGA sequences.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.