miR-148b reverses cisplatin-resistance in non-small cell cancer cells via negatively regulating DNA (cytosine-5)-methyltransferase 1(DNMT1) expression.

J Transl Med · 2015 · PMC4417300 · PMID 25927928

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highly significantno p-value reported

As shown in Figure 1 B, cotransfection of miR-148b mimics with the DNMT1 3′UTR reporter resulted in a decrease (40%) in luciferase activity and a highly significant decline in mRNA of DNMT1 in A549/DDP cells.

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