A single dose of a neuron-binding human monoclonal antibody improves brainstem NAA concentrations, a biomarker for density of spinal cord axons, in a model of progressive multiple sclerosis.

J Neuroinflammation · 2015 · PMC4418041 · PMID 25924771

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hedged sentence

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantP < 0.001actually significant

Fisher’s exact test showed this was highly significant (HIgM12 vs control IgM, P < 0.001; HIgM12 vs PBS, P < 0.001; and control IgM vs PBS, P = 0.39): 84% of mice treated with HIgM12 showed a positive response (Additional file 2 : Figure S2).

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