Suppression of the Insulin Receptors in Adult Schistosoma japonicum Impacts on Parasite Growth and Development: Further Evidence of Vaccine Potential.

japonicum , indicating its potential value as a transmission blocking vaccine candidate; we obtained highly significant reductions in faecal eggs (56–67%), stunting of adult worms (12–42%), and a reduction in the numbers of mature intestinal eggs (75%) in animals vaccinated with the L1 subdomain of SjIR-2 (SjLD2) recombinantly expressed in Escherichia coli compared with controls [ 17 ].

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