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Quantification of histone deacetylase isoforms in human frontal cortex, human retina, and mouse brain.

PLoS One · 2015 · PMC4427357 · PMID 25962138

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an increasing trendno p-value reported
HDAC5 and HDAC6 both showed an increasing trend of 47% and 31%, respectively.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.