A novel candidate region for genetic adaptation to high altitude in Andean populations.

Interestingly, in both Aymara and Quechua, when compared to the standard demographic model, Tajima’s D values are marginally significant (P values = 0.0568 and 0.0565, S2C Fig ) around chr10:82.0~82.3 Mb, and Fay and Wu’s H values are significant in both highlander groups in the same region (P values = 0.014 and 0.0212, S2D Fig ).

also in 26,082 other papers

With this threshold, five out of the six SNPs from the region on chr10:81.7~82.2 Mb stood out as highly significant in the HL-LL as well as the Aymara-Guarani comparisons ( Table 1 ).

also in 132,142 other papers