The random effects model had a slope of -0.236 (95% CI: -0.358–-0.114) and demonstrated a highly significant correlation of the number of C3_rs2230199 risk alleles with GA growth (P raw = 1.5x10 -4 ), which remained statistically significant after adjustment for multiple testing (P corrected = 0.0024).
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Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration.
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