Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors.

The proportional hazard assumption was studied by Schoenfeld partial residuals and their correlation with the rank order of failure times and by introducing time dependent interaction terms for the covariates in the model to detect a possible trend over time of the hazard ratio [ 16 , 17 ].

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