Although the energy substrates did not entirely prevent the above described AMPA-induced paralysis, its protective effect was highly significant, attaining 91 s in the rotarod performance at day 1, and then 66–76 s from day 4 to 7 (Figure 2 A).
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Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates.
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