Barely Significant
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Endogenous circadian regulation of pro-inflammatory cytokines and chemokines in the presence of bacterial lipopolysaccharide in humans.

Brain Behav Immun · 2015 · PMC4430446 · PMID 25452149

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a decreasing trendno p-value reported
an increasing trendno p-value reported
There was a significant main effect of time on MCP-1 ( p <0.01) and GM-CSF (p<0.05), under both CR and standard sleep-wake conditions ( Figure 2A and B ), showing a decreasing trend with time under baseline conditions but an increasing trend under CR conditions.

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