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Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality.

J Am Med Inform Assoc · 2015 · PMC4433365 · PMID 25053577

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an overall trendno p-value reported
Lung cancer and prostate cancer mortality was not significantly improved with metformin, although the HRs did show an overall trend toward reduced mortality.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.