Not surprisingly, a meta-analysis combining the results of the two randomized studies using Peto's method could not demonstrate any difference in the rate of thrombosis recurrence between the two regimens, although an almost significant excess thrombotic risk was observed with high-intensity anticoagulation [ 20 ].
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Treatment of Thrombotic Antiphospholipid Syndrome: The Rationale of Current Management-An Insight into Future Approaches.
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