Collectively, ASIC1a deletion caused a highly significant reduction in the magnitude of LTP in BLA-PNs and CeM-LTB neurons ( Fig. 3e ), both of which exhibited the highest ASIC current density, whereas this deletion had little effect on LTP in CeM-ES and CeL neurons that expressed relatively low levels of ASICs.
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ASIC-dependent LTP at multiple glutamatergic synapses in amygdala network is required for fear memory.
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