Barely Significant
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Thymidylate Synthase as a Predictive Biomarker for Pemetrexed Response in NSCLC.

Lung Cancer Int · 2013 · PMC4437388 · PMID 26316940

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a positive trendno p-value reported
Thus, although clinical response rates were not significant, there was a positive trend noted for low-TS patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.