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Molecular Modification of Metadherin/MTDH Impacts the Sensitivity of Breast Cancer to Doxorubicin.

PLoS One · 2015 · PMC4437901 · PMID 25993398

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The mRNA expression of MTDH gene in breast cancer cells revealed an increasing trend from low to high level, as 1.11 ± 0.10 in MDA-MB-231 cells, 17.58 ± 3.11 in MCF-7 cells, 49.66 ± 10.77 in MDA-MB-435S cells, and 201.74 ± 14.57 in MCF-7/ADR cells ( Fig 1A ).

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