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Tumor grafting induces changes of gut microbiota in athymic nude mice in the presence and absence of medicinal Gynostemma saponins.

PLoS One · 2015 · PMC4439139 · PMID 25992551

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an increasing trendno p-value reported
The pyrosequencing data indicated that the Bacteroidetes / Firmicutes ratio showed an increasing trend after 10 d of GpS treatment in xenograft mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.