The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis.

PLoS Negl Trop Dis · 2015 · PMC4441390 · PMID 26001191

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highly significantno p-value reported

In contrast, cells expressing the Y18A, Y80A, and Y129A mutant proteins showed a highly significant reduction in their ability to increase cytoplasmic heme levels, at both concentrations of heme tested.

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