The benefit and burden of cancer screening in Li-Fraumeni syndrome: a case report.

Yale J Biol Med · 2015 · PMC4445439 · PMID 26029016

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may be significantno p-value reported

While the intent of aggressive cancer screening is to help patients enjoy a prolonged, healthy life with minimal cancer burden, there may be significant trade-off in psychosocial burden for some patients related to aggressive surveillance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.