Barely Significant
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Regulation of indoleamine 2,3-dioxygenase in primary human saphenous vein endothelial cells.

J Inflamm Res · 2015 · PMC4446016 · PMID 26056484

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highly significantno p-value reported
The endothelial cell is one of the first contacts of an activated lymphocyte, hence whether it has the mechanistic capability to increase IDO expression and regulate the immune response is highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.