Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae.

Mol Ecol · 2015 · PMC4447564 · PMID 25865270

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highly significantP = 4.5 × 10 −22actually significant

We detected a highly significant difference (heteroscedastic t -test, t 38 = 20.4, P = 4.5 × 10 −22 ) in estimated copy number between 119S/S (mean ± 95%CI = 4.75 ± 0.32) and 119G/G (mean = 1.12 ± 0.09) individuals (Fig. 5 A).

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