Heat shock protein (HSP70) as a marker of epithelial dysplasia in oral dysplastic lesions: A clinicopathological study.

, in 1998 reported significant association between HSP70 overexpression and habit of consumption of tobacco and/or betel with areca nut and found a positive trend in the incidence of HSP70 overexpressing premalignant cases across the groups: Nonconsumers, betel and arecanut consumers and consumers of tobacco as well as betel and areca nut.[ 7 ] In the present study, all the patients in case group were either tobacco chewers or smokers.

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