Nevertheless, a recently published systematic review and meta-analysis, comprising of eight original articles with a total of 21,064 participants and 2,053 CHD events [ 33 ] reported a positive association between leptin and incident CHD after adjustment for age, sex, lipids, blood pressure, and BMI, although the association did not quite reach statistical significance [ 33 ].
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Adipocytokines, C-reactive protein, and cardiovascular disease: a population-based prospective study.
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