Comprehensive validation of published immunohistochemical prognostic biomarkers of prostate cancer -what has gone wrong? A blueprint for the way forward in biomarker studies.

Br J Cancer · 2015 · PMC4453620 · PMID 25422912

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

of borderline significanceP =0.051so close (0.05 < p ≤ 0.1)

In univariate Cox analyses, only nine markers were found significant (nuclear and stromal AR, CB1R, CRGA, E-Cadherin, NFkB, p21, p27, and PSMA), CD10 was of borderline significance ( P =0.051) and Ki-67 dropped out.

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