Barely Significant
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MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

Br J Cancer · 2015 · PMC4453955 · PMID 25668009

Europe PMCDOI
1
hedged sentence
0.0505
closest p · 1.0× alpha
0.0505
boldest claim

The sentences

a statistical trendP =0.0505so close (0.05 < p ≤ 0.1)
Neither MDM2 ( P =0.54) nor P14/ARF ( P =0.27) mRNA expression showed a significant correlation with respect to the patients' age. P14/ARF mRNA expression showed no significant correlation with respect to sample age ( P =0.089). MDM2 mRNA expression showed a statistical trend with respect to sample age ( P =0.0505), but the positive rho-value (rho=0.28) indicated a direct correlation between sample age and mRNA leading to the assumption that with increasing age of the sample the mRNA amount would increase.

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