Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells.

Cell Death Dis · 2014 · PMC4454314 · PMID 25118938

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might be significantno p-value reported

44 Inhibition of Notch1 signaling suppressed CdCl 2 -induced cellular damage less significantly in human hepatoma HepG2 cells and human neuroblastoma SH-SY5Y cells than in HK-2 cells ( Supplementary Figure S7 ), indicating that the pathological significance of cadmium-induced activation of Notch1 signaling is different among cell types and might be significant in renal proximal tubular cells.

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