Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors.

PLoS One · 2015 · PMC4454515 · PMID 26039708

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

very close to statistical significancep = 0.055so close (0.05 < p ≤ 0.1)

The association of CNV or mutation with OS within the whole PI3KCA/AKT pathway was very close to statistical significance (p = 0.055) ( Fig 1 ).

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marginally significantno p-value reported

Among other individually found genomic alterations, TP53 mutations (p=0.07), mTOR gain (p=0.07) and PTEN overexpression (p=0.08) have a marginally significant negative impact on OS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.