Omitting the smoking controls, global hypothesis tests followed by a closed testing procedure show highly significant differences between the three study groups in the variables ‘presence of NETs’ (in large amounts or minor traces), ‘percentage of NET-covered area’, and ‘FEV1’ (overall type 1 error rate α < 0.001).
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Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation.
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