highly significantP<1 x 10 −35
rs13038305 in relation to plasma cystatin C and creatinine based measures of GFR In the MDC-CC, each copy of the major allele of rs13038305 was associated with a highly significant (P<1 x 10 −35 ) approximately one third of a SD increase of plasma concentration of cystatin C both in model 1 and model 2.