Establishment of an interleukin-1β-induced inflammation-activated endothelial cell-smooth muscle cell-mononuclear cell co-culture model and evaluation of the anti-inflammatory effects of tanshinone IIA on atherosclerosis.

Mol Med Rep · 2015 · PMC4464412 · PMID 25936371

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an increasing trendno p-value reported

The levels of MMP2 and IL-6 in the SMC supernatant exhibited an increasing trend between 3 and 9 days in the co-culture system, and the increase in MMP2 after 6 days was statistically significant ( Fig. 2C ).

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