EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival.

PLoS Pathog · 2015 · PMC4466530 · PMID 26070070

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fell slightly short of significanceno p-value reported

As shown in Fig 6B , we observed a significant (p<0.05) reduction in the level of expression of all the predicted mRNA targets with the exception of the TP53INP1/miR-BART22 combination, where the observed reduction in mRNA expression fell slightly short of significance.

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did not achieve significanceno p-value reported

We also observed a significant reduction in apoptosis in one of the two cell lines expressing an amiRNA specific for OCT1 and CREBBP, with the other cell line showing a trend towards lower apoptosis that did not achieve significance due to a high standard deviation between assay replicates.

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