Moreover, the fact that even this relatively “blurred” characterization of the spatiotemporal organization of whole-brain resting-state brain activation captures highly significant effects of both gender and mental illness indicates that the 4D frequency domain is a powerful source of information about normative and group-specific brain function.
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Multidimensional frequency domain analysis of full-volume fMRI reveals significant effects of age, gender, and mental illness on the spatiotemporal organization of resting-state brain activity.
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