Epigenetic modifications of the glucocorticoid receptor gene are associated with the vulnerability to psychopathology in childhood maltreatment.

Interestingly, methylation of the same CpG site also displayed a highly significant positive correlation to BPD symptoms ( Figure 2 , Supplementary Table S2 ).

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While the former did not influence BPD symptoms, there was a statistical trend towards an influence of age on BPD symptoms ( β sex =−0.2, P sex >0.1, β age =0.2, P age ⩽0.1).

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