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Evolutionary Dynamics of Tat in HIV-1 Subtypes B and C.

PLoS One · 2015 · PMC4472691 · PMID 26087118

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an increasing trendno p-value reported
There was an exponential escalation in the occurrence of infections from 1960–1970 to the early 1990s with an increasing trend up to the 2010s ( Fig 1B ).

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