Firstly, large-scale drug screening (130 compounds) in >600 human cancer cell lines identified a highly significant association between EWS-FLI1 , the hallmark translocation of Ewing sarcoma, and sensitivity to the olaparib.
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Firstly, large-scale drug screening (130 compounds) in >600 human cancer cell lines identified a highly significant association between EWS-FLI1 , the hallmark translocation of Ewing sarcoma, and sensitivity to the olaparib.