Impact of different controlled ovarian stimulation protocols on the physical and psychological burdens in women undergoing in vitro fertilization/intra cytoplasmic sperm injection.

An interventional, noninferiority study conducted with the primary outcome measure of pregnancy and term live birth within 1-year of randomization, total cost per couple and patient discomfort compared the two protocols similar to the present study that is, the mild treatment strategy (GnRH Antagonist protocol and single embryo transfer [ET]) and conventional treatment (GnRH Agonist protocol) for IVF.[ 15 ] It was also noted that depression and anxiety scores showed an increasing trend over IVF cycle one to cycle four.

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