Comparative Evaluation of Sustained Release Collagen Device Containing 5% Metronidazole (Metrogene) along With and Without Scaling and Root Planing at Regular Intervals with Treatment of Chronic Periodontitis: A Case Control Study.

14 When it is compared between control and experiment site B, the difference was statistically highly significant, which is consistent with the findings of Aziz Gandour et al . 19 and Lindhen et al . 14 The mean reduction in pocket depth between experimental site A and experimental site B shows a statistically highly significant difference which strongly supports the findings of Aziz Gandour et al . 19 and Hitzig et al. , 6 who observed a dramatic reduction in probing pocket depth after Metronidazole therapy along with mechanical debridement from 0 th day to the end of the study.

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