Structural and Mechanical Improvements to Bone Are Strain Dependent with Axial Compression of the Tibia in Female C57BL/6 Mice.

PLoS One · 2015 · PMC4482632 · PMID 26114891

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an increasing trendno p-value reported

In addition to the effect of strain level, there was also a significant main effect of loading in BV/TV (p = 0.013) with an increasing trend in the loaded limb.

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failed to reach significanceno p-value reported

In the current study, structural- and tissue-level energy dissipation were also increased, and although total deformation and strain to failure trended up, they failed to reach significance in any group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.