The prognostic impact of mutations in spliceosomal genes for myelodysplastic syndrome patients without ring sideroblasts.

Consistent with findings by Thol et al ., who reported that SRSF2 mutations were associated with an increased risk of progression to AML [ 18 ], we observed a somewhat significant impact of the SRSF2 mutation on the progression time to AML transformation (Figs. 2i and 3d ).

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